Plant Production Manager

Date: Jul 15, 2019

Location: Brantford, ON, CA, N3T 6B8

Company: Apotex


Apotex is a proudly Canadian, global pharmaceutical company that produces high-quality, affordable medicines (both generic and innovative pharmaceuticals) for patients around the world. We are the 7th largest generic pharmaceutical company globally with more than 12,000 employees and estimated sales of approximately $3 billion. Our fully integrated operation is comprised of four lines of business: Global Generics; Apobiologix; Global Active Pharmaceutical Ingredients (API); and ApoPharma (Innovative Products). With our worldwide manufacturing sites, Apotex can produce up to 24 billion dosages per year. We produce 300 medicines in 4,000 dosages and formats that are exported to 115 countries. Apotex will spend $2 billion over the next 10 years on research and development.


Job Summary

The Production Manager is a hands-on leader with excellent problem solving skills and a drive for success. Reporting to the Vice Present & General Manager, the incumbent is responsible for overseeing the reliable and efficient daily production of active pharmaceutical ingredients (APIs). Ensure efficient collaboration and co-ordination between relevant departments. 

Job Responsibilities

Operations Manager

  • Responsible for overseeing daily activities of the Production group and ensure that all production operations personnel work in compliance with cGMP guidelines, departmental and company policies and Government regulations.
  • Responsible for investigating and dealing with violations against company policies and procedures.
  • Achieve and improve Production KPI’s and adherence to schedule by monitoring daily production downtime/operations efficiency, assisting in troubleshooting process and equipment operability issues, identify root causes and implement efficient and simple solutions.
  • Work closely with Engineering on the development and optimization of maintenance programs, shutdown maintenance schedules, new equipment specifications for capital projects and existing equipment modifications.
  • Monitor and control overall plant operating expenses. Responsible for drafting key development, equipment requirements or upgrades. Identify areas of automation and cost reductions.
  • Promote and develop a sustainable continuous improvement environment that promotes innovation and reduces complexities within Production Operations by creating an environment conducive to change using Lean tools.


People Development

  • Develop a team that is highly respected and engaged by creating a transparent, cooperative and trustworthy work environment through timely performance feedback, open communication and coaching to resolve functional and personnel issues.
  • Participate and lead performance conversations with employees, including monthly one on ones, to connect on performance; check in on employee’s progress toward achieving Objectives, offer support and remove barriers; and, communicate and revisit performance expectations to reinforce and encourage high performance culture and a safe working environment for all employees
  • Actively develop high potential employees for the next generation of leaders through mentorship, development planning, stretch assignments and cross-training opportunities.


Safety and Compliance

  • Encourage a culture of compliance as required by cGMPs, Health Authority’ regulations, government agencies, and company standards / policies. Support all site audits and inspections.
  • Ensure Environmental, Health & Safety compliance by: actively searching for potential risks and mitigating them; making the necessary reports in case of incidences; and implementing corrective and preventive measures to ensure the wellbeing of employees, as well as compliance with necessary regulations.
  • Responsible for the overall cGMP compliance of all production facilities at Pharmachem and maintains those facilities in an inspection ready state. Organize and implement audit follow-up activities, deviations, corrective actions, preventative actions (CAPA) related to production.



  • Be a role model and change agent. Exude optimism. Champion company objectives and support peers. Live the Apotex values of Collaboration, Courage, Passion and perseverance every day. Be proactive and hold peers accountable.
  • Utilize open, honest, two way communication to build trust-based relationships with employees, business partners and direct leader while continuously improving leadership capabilities by personally seeking feedback and development.
  • Work consistently as a member of the management team in a professional, positive and accountable manner. Serve as a mentor to develop other leaders across the site.

Job Requirements

  • Minimum Bachelor degree in Chemistry or Chemical Engineering preferably with a background in organic synthesis.
  • Knowledge of cGMP and Active Pharmaceutical Ingredient manufacturing is an asset.
  • Demonstrated success in driving and leading change with continuous improvement and a dedication to craftsmanship and putting safety and quality first.
  • Sound knowledge of Good Manufacturing Practice (GMP), and experience in LEAN, OEE or other continuous improvement methodologies.
  • Thorough knowledge of production equipment, process unit operations and industrial facility systems
  • Sound technical, hands-on process knowledge and expertise in the pharmaceutical industry. Including pharmaceutical regulations from FDA, EU, ICH and PICs guidelines.
  • Unquestionable integrity, dedication to safety and accountable.
  • Excellent critical thinking skills to anticipate the long term impact of decisions and take a broad approach to problem solving
  • Strong business acumen with demonstrated ability to manage multiple stakeholders.
  • At least 10 years’ experience in an industrial chemical production environment with demonstrated leadership skills and Managerial experience



At Apotex, we are committed to fostering an inclusive, accessible work environment, where all employees feel valued, respected and supported.
Apotex offers accommodation for applicants with disabilities as part of its recruitment process. If you are contacted to arrange for an interview or testing, please advise us if you require an accommodation.


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